Berkeley record store clerk Nick Brady (Jonathan Scarfe) begins to experience strange visions from an entity he calls VALIS that cause him to uproot his family and move to Los Angeles where he becomes a successful music company executive. With the help of best friend, science-fiction writer Philip K. Dick himself (Shea Whigam) and a mysterious woman named Silvia (Alanis Morissette), Nick finds himself drawn into a dangerous political-mystical conspiracy of cosmic proportions. The story is set in an alternate reality America circa 1985 under the authoritarian control of President Fremont, a Nixon-like clone (Scott Wilson).

Centers on Missy's adopted daughter Belinda Tyler as she follows her dream. Belinda wants to be a doctor, but this time period does not look kindly on women with careers, especially one in the medical field. But Belinda is a strong-minded woman and deeply wants a career as a doctor. She manages to prove her abilities while assisting the local doctor and caring for an old woman who recently experienced a stroke. Belinda nurses her back to health and helps her regain the use of her arm again. Belinda also meets the nephew of their deceased neighbor. Drew comes to town to get his uncle's farm in shape to sell. After that he intends on returning to New York to join his father's law practice. He has no desire to stay in this small, unsophisticated town. But after meeting Belinda he has second thoughts. Belinda also feels something for Drew, but she is conflicted because she wants to be a doctor...

Michael returns home from military school to find his mother happily in love and living with her new boyfriend. As the two men get to know each other, he becomes more and more suspicious of the man who is always there with a helpful hand.